Recently, Nature published online a white paper titled "π-HuB: the Proteomic Navigator of the Human Body," initiated by Chinese scientists and co-signed by scientists from 18 countries. This marks the first time Nature has published a white paper on a global big science project led by Chinese researchers.
On December 17, the symposium of the π-HuB project was held in Guangzhou. "More than 20 years after the completion of the Human Genome Project, while it has catalyzed the global bioeconomy's growth and prosperity, its impact on human health and the understanding of life and death has not met initial expectations. The human body consists of 37 trillion cells, and it is the dynamic changes in proteins that hold the key to understanding life, aging, disease and death," He Fuchu, the project's chief scientist, said.
The publication of the π-HuB white paper in Nature highlights China's growing status, academic influence and organizational leadership in global life sciences. It also showcases the significant contributions of China's proteomics research in advancing global scientific collaboration and building a global community of health and shared future for all, according to the experts at the symposium.
The π-HuB project aims to decode the human body on a higher level than the Human Genome Project by focusing on a "real-time panoramic map" of the proteome. It is anticipated to deepen our understanding of human biology, facilitate disease risk assessment, early diagnosis, optimal treatment strategies and the development of precision medicine. It will significantly advance proteomics technologies, leading to new diagnostic methods, therapeutic targets and revolutionary approaches to health management.
This initiative aims to usher in a transformative era of healthcare, shifting the focus toward proactive health management. According to He, the project will fully integrate artificial intelligence and big data analytics to transform data and information into knowledge and wisdom.
As of now, the π-HuB project has garnered support from over 114 top scientific teams from more than 20 countries and regions, forming a global collaborative network.